Hybridoma cell line producing IR 83-7 antibodies raised against the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cause enhancement of insulin binding and has been used in immunoprecipitation assays.

This reagent is available to license for internal research use only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/