Human insulin receptor monoclonal antibody IR 25-49

Code: AB30

Hybridoma cell line producing IR 25-49 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react weakly with rabbit but not bovine, porcine, ovine, rat or mouse insulin receptors. It has been shown to cause >80% inhibition of insulin binding and has been used in immunoprecipitation and blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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