Hybridoma cell line producing IR 18-44 antibodies raised against the beta subunit of the human insulin receptor which are mouse monoclonal antibodies of the IgG2b isotype. Has has been shown to cause up to 50% inhibition of insulin binding and has been used in western blots, immunoprecipitation and blocking assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/