Hybridoma cell line producing IR 18-146 antibodies raised against the extracellular domain of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react very weakly with bovine, porcine and ovine but not rabbit, rat or mouse insulin receptors. It causes enhancement of insulin binding and has been used in immunoprecipitation assays.
Publications:
Biochem J (1986) 235, 199
Biochem J (1987) 242, 123
EMBO J (1987) 6, 4003
Biochem J (1990) 268, 615
J Biol Chem (1990) 265, 9970. www.jbc.org/
J Biol Chem (1990) 265, 13248. www.jbc.org/
PNAS (1991) 88, 9858. www.pnas.org/
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