Human insulin receptor monoclonal antibody IR 18-146

Code: AB32

Hybridoma cell line producing IR 18-146 antibodies raised against the extracellular domain of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react very weakly with bovine, porcine and ovine but not rabbit, rat or mouse insulin receptors. It causes enhancement of insulin binding and has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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