Hybridoma cell line producing IR 47-9 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react with bovine, porcine, ovine (and weakly with rabbit), but not with rat or mouse insulin receptors. It has been shown to cause >80% inhibition of insulin binding and has been used in blocking assays.
Publications:
Biochem J (1986) 235, 199
Biochem J (1987) 242, 123
EMBO J (1987) 6, 4003
Biochem J (1990) 268, 615
J Biol Chem (1990) 265, 9970. www.jbc.org/
J Biol Chem (1990) 265, 13248. www.jbc.org/
PNAS (1991) 88, 9858. www.pnas.org/
Enquiry for Human insulin receptor monoclonal antibody IR 47-9
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