BG4 anti-DNA/RNA G-quadruplex antibody (and related small molecules)

Code: AB-0268

BG4 anti-DNA/RNA G-quadruplex antibody is an engineered, structure-specific scFv probe that binds with high selectivity and low nanomolar affinity to DNA and RNA G-quadruplex structures as described in the following publications by Biffi, Antonio, Tannahill, McCafferty and Balasubramanian:

Nat. Chem. 5, 182–186 (2013)

Nat. Chem. 6, 75–80 (2014)

Angew. Chem. Int. Ed. Engl. 54, 910-913 (2015)

Nat. Genetics, 48,1267–1272 (2016)

The nucleic acid stabiliser molecules pyridostatin (PDS) and carboxy-pyridostatin described in the above and related papers are also available for licensing.

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