Available reagents

Licensing for the research community

Cell lines, antibodies, proteins, DNA constructs, small molecules and other research tools generated by scientists at the University of Cambridge play a key role in laboratory research. There is a wide range of research reagents available for commercial licensing through Cambridge Enterprise. The selection is constantly changing, so please contact us directly with your specific needs.

Non-exclusive licences with standard terms and conditions are available for available reagents.

Human insulin-like growth factor-1 receptor monoclonal antibody IGF-1R 24-60

1 September, 2011 | Monoclonal hybridomas Code: AB35
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Hybridoma cell line producing IGF-1R 24-60 antibodies raised against the human insulin-like growth factor receptor (epitope 184-283) which are mouse monoclonal antibodies of the IgG2a isotype. Has been shown to cause >80% inhibition of IGF binding and has been used for immunoprecipitation and blocking assays.

Publications:

J Biol Chem (1992) 267, 12955. www.jbc.org/

J Biol Chem (1993) 268, 1087. www.jbc.org/

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Human insulin-like growth factor-1 receptor monoclonal antibody IGF-1R 26-3

1 September, 2011 | Monoclonal hybridomas Code: AB39
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Hybridoma cell line producing IGF-1R 26-3 antibodies raised against the human insulin-like growth factor receptor (epitope 283-440 or 586-908) which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to enhance IGF binding and has been used for immunoprecipitation and immunohistochemistry.

Publications:

J Biol Chem (1992) 267, 12955. www.jbc.org/

J Biol Chem (1993) 268, 1087. www.jbc.org/

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Human insulin receptor monoclonal antibody IR 18-146

1 September, 2011 | Monoclonal hybridomas Code: AB32
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Hybridoma cell line producing IR 18-146 antibodies raised against the extracellular domain of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react very weakly with bovine, porcine and ovine but not rabbit, rat or mouse insulin receptors. It causes enhancement of insulin binding and has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Human insulin receptor monoclonal antibody IR 18-40

1 September, 2011 | Monoclonal hybridomas Code: AB31
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Hybridoma cell line producing IR 18-40 antibodies raised against the extracellular domain of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react weakly with bovine, porcine, ovine and rabbit, but not rat or mouse insulin receptors. It has been shown to cause up to 50% inhibition of insulin binding and has been used in immunoprecipitation and blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 18-40

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Human insulin receptor monoclonal antibody IR 25-49

1 September, 2011 | Monoclonal hybridomas Code: AB30
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Hybridoma cell line producing IR 25-49 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react weakly with rabbit but not bovine, porcine, ovine, rat or mouse insulin receptors. It has been shown to cause >80% inhibition of insulin binding and has been used in immunoprecipitation and blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 25-49

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Human insulin receptor monoclonal antibody IR 47-9

1 September, 2011 | Monoclonal hybridomas Code: AB2
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Hybridoma cell line producing IR 47-9 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react with bovine, porcine, ovine (and weakly with rabbit), but not with rat or mouse insulin receptors. It has been shown to cause >80% inhibition of insulin binding and has been used in blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 47-9

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Human insulin receptor monoclonal antibody IR 83-12

1 September, 2011 | Monoclonal hybridomas Code: AB41
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Hybridoma cell line producing IR 83-12 antibodies raised against the extracellular domain of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react with bovine, porcine, ovine and rabbit, but not with rat or mouse insulin receptors. It has been shown to enhance insulin binding and has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 83-12

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Human insulin receptor monoclonal antibody IR 83-22

1 September, 2011 | Monoclonal hybridomas Code: AB42
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Hybridoma cell line producing IR 83-22 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react very weakly with bovine, porcine and ovine, but not rabbit, rat or mouse insulin receptors. It has been shown to cause >80% inhibition of insulin binding and has been used in immunoprecipitation and blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. http://www.jbc.org/

J Biol Chem (1990) 265, 13248. http://www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 83-22

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Human insulin receptor monoclonal antibody IR CT-3

1 September, 2011 | Monoclonal hybridomas Code: AB5
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Hybridoma cell line producing IR CT-3 antibodies raised against the C-terminal portion of the human insulin receptor beta subunit, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cross react with rat and mouse insulin receptors and has been used in western blots and immunoprecipitation assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1986) 235:199

Biochem J (1987) 242:123

EMBO J (1987) 6:4003

Biochem J (1990) 268:615

J Biol Chem (1990) 265:9970. http://www.jbc.org/

J Biol Chem (1990) 265:13248 http://www.jbc.org/

PNAS (1991) 88:9858. http://www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR CT-3

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 18-42

1 September, 2011 | Monoclonal hybridomas Code: AB76
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Hybridoma cell line producing IR 18-42 antibodies raised against the beta subunit N-terminal region of the human insulin receptor, which are mouse monoclonal antibodies of the IgG2b isotype. Has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235:199

Biochem J (1987) 242:123

EMBO J (1987) 6:4003

Biochem J (1990) 268:615

J Biol Chem (1990) 265:9970 http://www.jbc.org/

J Biol Chem (1990) 265:13248 http://www.jbc.org/

PNAS (1991) 88:9858. http://www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 18-42

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 18-43

1 September, 2011 | Monoclonal hybridomas Code: AB77
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Hybridoma cell line producing IR 18-43 antibodies raised against the beta subunit N-terminal region of the human insulin receptor, which are mouse monoclonal antibodies of the IgG2a isotype. Has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235:199

Biochem J (1987) 242:123

EMBO J (1987) 6:4003

Biochem J (1990) 268:615

J Biol Chem (1990) 265:9970. http://www.jbc.org/

J Biol Chem (1990) 265:13248. http://www.jbc.org/

PNAS (1991) 88:9858. http://www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 18-43

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 18-45

1 September, 2011 | Monoclonal hybridomas Code: AB78
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Hybridoma cell line producing IR 18-45 antibodies raised against the beta subunit N-terminal region of the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been used in immunoprecipitation assays.

Publications:

Biochem J (1986) 235:199

Biochem J (1987) 242:123

EMBO J (1987) 6:4003

Biochem J (1990) 268:615

J Biol Chem (1990) 265:9970. http://www.jbc.org/

J Biol Chem (1990) 265:13248. http://www.jbc.org/

PNAS (1991) 88:9858. http://www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 18-45

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Sheep immunoglobulin G monoclonal antibody SIg 482

1 September, 2011 | Monoclonal hybridomas Code: AB59
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Hybridoma cell line producing SIg 482 antibodies raised against sheep immunoglobulin G which are mouse monoclonal antibodies of the IgG isotype. Has been used in western blots, affinity chromatorgraphy and ELISA.

Publications:

Biochem J 1984, 219, 647–654

J Neurochem 1987, 48, 622–630

Nature 1987, 327, 232–234

J Neurochem 1990, 55, 31–38

J Neurochem 1993, 60, 219–227

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Enquiry for Sheep immunoglobulin G monoclonal antibody SIg 482

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Sheep immunoglobulin G monoclonal antibody SIg 743

1 September, 2011 | Monoclonal hybridomas Code: AB60
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Hybridoma cell line producing SIg 743 antibodies raised against sheep immunoglobulin G which are mouse monoclonal antibodies of the IgG isotype. Has been used in western blots, affinity chromatorgraphy and ELISA.

Publications:

Biochem J 1984, 219, 647–654

J Neurochem 1987, 48, 622–630

Nature 1987, 327, 232–234

J Neurochem 1990, 55, 31–38

J Neurochem 1993, 60, 219–227

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Enquiry for Sheep immunoglobulin G monoclonal antibody SIg 743

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Mouse Thy-1 monoclonal antibody YBM 29.2.1

1 September, 2011 | Monoclonal hybridomas Code: AB11
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Hybridoma cell line producing YBM 29.2.1antibodies raised against mouse Thy-1, which are rat monoclonal antibodies of the IgG2c isotype. Has been used in flow cytometry and in vitro T cell depletion studies.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061

Cobbold S. & H. Waldmann (1986) Transplantation 41, 634

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Enquiry for Mouse Thy-1 monoclonal antibody YBM 29.2.1

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Mouse CD8 (lyt-2) monoclonal antibody YTS 169.4.2.1

1 September, 2011 | Monoclonal hybridomas Code: AB14
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Hybridoma cell line producing YTS 169.4.2.1 antibodies raised against mouse CD8 (lyt-2), which are rat monoclonal antibodies of the IgG2b isotype. Has been used in CD8 subset depletion in vivo and flow cytometry studies.

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Enquiry for Mouse CD8 (lyt-2) monoclonal antibody YTS 169.4.2.1

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Mouse CD4 epitope A monoclonal antibody YTS 191.1.2

1 September, 2011 | Monoclonal hybridomas Code: AB16
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Hybridoma cell line producing YTS 191.1.2 antibodies raised against mouse CD4 epitope A which are rat monoclonal antibodies of the IgG2b isotype. Has been used in in vivo depleting and flow cytometry studies.

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Herpes Simplex Virus Glycoprotein D monoclonal antibody AP12 (anti-HSV gD)

1 September, 2011 | Monoclonal hybridomas Code: AB90
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Hybridoma cell line producing AP12 antibodies raised against Herpes Simplex Virus Type-1 and Type-2 envelope protein Glycoprotein D, which are mouse monoclonal antibodies of the IgG1 isotype. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in western blots. The antibody epitope is well characterised by binding competition assays and by sequencing of antibody escape mutants.

 

Publications:

Minson A.C., Hodgman T.C., Digard P., Hancock D.C., Bell S.E., Buckmaster E.A.
An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
J Gen Virol. 1986 67:1001–13.
http://vir.sgmjournals.org/

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Herpes Simplex Virus Glycoprotein D monoclonal antibody LP14 (anti-HSV gD)

1 September, 2011 | Monoclonal hybridomas Code: AB89
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Hybridoma cell line producing LP14 antibodies raised against Herpes Simplex Virus Type-1 and Type-2 envelope protein Glycoprotein D, which are mouse monoclonal antibodies of the IgG2a isotype. Can be used to neutralise virus in the absence of Complement. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Can be used to detect protein by western blot. The linear epitope has been defined for this antibody.

A non-exclusive licence with standard terms and conditions is available for this reagent.

Publications:

Minson A.C., Hodgman T.C., Digard P., Hancock D.C., Bell S.E., Buckmaster E.A. An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
J Gen Virol. 1986 67:1001–13.
http://vir.sgmjournals.org/

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Enquiry for Herpes Simplex Virus Glycoprotein D monoclonal antibody LP14 (anti-HSV gD)

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Herpes Simplex Virus Glycoprotein D monoclonal antibody AP7 (anti-HSV gD)

1 September, 2011 | Monoclonal hybridomas Code: AB92
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Hybridoma cell line producing AP7 antibodies raised against Herpes Simplex Virus Type-1 and Type-2 envelope protein Glycoprotein D, which are mouse monoclonal antibodies of the IgG2a isotype. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in western blots. The antibody epitope is well characterised by binding competition assays and by sequencing of antibody escape mutants.

 

Publications:

Minson A.C., Hodgman T.C., Digard P., Hancock D.C., Bell S.E., Buckmaster E.A. An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
J Gen Virol. 1986 67:1001–13.
http://vir.sgmjournals.org/

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Enquiry for Herpes Simplex Virus Glycoprotein D monoclonal antibody AP7 (anti-HSV gD)

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Herpes Simplex Virus Glycoprotein H monoclonal antibody LP11 (anti-HSV gH)

1 September, 2011 | Monoclonal hybridomas Code: AB103
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Hybridoma cell line producing LP11 antibodies raised against Herpes Simplex Virus Type-1 envelope protein Glycoprotein H, which are mouse monoclonal antibodies of the IgG2a isotype. Strongly neutralises virus in the absence of Complement. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in western blots. Produces antibodies with unique anti-gH neutralising properties.

 

Publications:

Buckmaster E.A., Cranage M.P., McLean C.S., Coombs R.R., Minson A. The use of monoclonal antibodies to differentiate isolates of herpes simplex types 1 and 2 by neutralisation and reverse passive haemagglutination tests.
J Med Virol. 1984 13:193–202.
http://eu.wiley.com/WileyCDA/WileyTitle/productCd-JMV.html

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Human insulin-like growth factor 1 receptor monoclonal antibody IGF-1R 24-31

1 September, 2011 | Monoclonal hybridomas Code: AB6
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Hybridoma cell line producing IGF-1R 24-31 antibodies raised against human insulin-like growth factor 1 receptor (283-440 or 586-908 epitope), which are mouse monoclonal antibodies of the IgG1 isotype. Has been used in immunoprecipitation and blocking studies and causes

This reagent is available to license for internal research only.

Publications:

J Biol Chem (1992) 267: 12955. www.jbc.org/

J Biol Chem (1993) 268: 1087. www.jbc.org/

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Human insulin receptor monoclonal antibody IR CT-1

1 September, 2011 | Monoclonal hybridomas Code: AB4
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Hybridoma cell line producing IR CT-1 antibodies raised against the C-terminal portion of the human insulin receptor beta subunit, which are mouse monoclonal antibodies of the IgG1 isotype. Has been used in western blots and immunoprecipitation assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1992) 288, 195

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Human insulin receptor monoclonal antibody IR 83-14

1 September, 2011 | Monoclonal hybridomas Code: AB7
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Hybridoma cell line producing IR 83-14 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG2a isotype. Has been shown to cause >80% inhibition of insulin binding and has been used in immunoprecipiatation and blocking assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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