Available reagents

Licensing for the research community

Cell lines, antibodies, proteins, DNA constructs, small molecules and other research tools generated by scientists at the University of Cambridge play a key role in laboratory research. There is a wide range of research reagents available for commercial licensing through Cambridge Enterprise. The selection is constantly changing, so please contact us directly with your specific needs.

Non-exclusive licences with standard terms and conditions are available for available reagents.

Herpes Simplex Virus Glycoprotein D monoclonal antibody LP14 (anti-HSV gD)

1 September, 2011 | Monoclonal hybridomas Code: AB89
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Hybridoma cell line producing LP14 antibodies raised against Herpes Simplex Virus Type-1 and Type-2 envelope protein Glycoprotein D, which are mouse monoclonal antibodies of the IgG2a isotype. Can be used to neutralise virus in the absence of Complement. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Can be used to detect protein by western blot. The linear epitope has been defined for this antibody.

A non-exclusive licence with standard terms and conditions is available for this reagent.

Publications:

Minson A.C., Hodgman T.C., Digard P., Hancock D.C., Bell S.E., Buckmaster E.A. An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
J Gen Virol. 1986 67:1001–13.
http://vir.sgmjournals.org/

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Enquiry for Herpes Simplex Virus Glycoprotein D monoclonal antibody LP14 (anti-HSV gD)

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Herpes Simplex Virus Glycoprotein D monoclonal antibody AP7 (anti-HSV gD)

1 September, 2011 | Monoclonal hybridomas Code: AB92
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Hybridoma cell line producing AP7 antibodies raised against Herpes Simplex Virus Type-1 and Type-2 envelope protein Glycoprotein D, which are mouse monoclonal antibodies of the IgG2a isotype. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in western blots. The antibody epitope is well characterised by binding competition assays and by sequencing of antibody escape mutants.

 

Publications:

Minson A.C., Hodgman T.C., Digard P., Hancock D.C., Bell S.E., Buckmaster E.A. An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
J Gen Virol. 1986 67:1001–13.
http://vir.sgmjournals.org/

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Enquiry for Herpes Simplex Virus Glycoprotein D monoclonal antibody AP7 (anti-HSV gD)

Reagents Enquiry

To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Herpes Simplex Virus Glycoprotein H monoclonal antibody LP11 (anti-HSV gH)

1 September, 2011 | Monoclonal hybridomas Code: AB103
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Hybridoma cell line producing LP11 antibodies raised against Herpes Simplex Virus Type-1 envelope protein Glycoprotein H, which are mouse monoclonal antibodies of the IgG2a isotype. Strongly neutralises virus in the absence of Complement. Works well for immunofluorescence (IF) on fixed specimens and for immunoprecipitiation (IP) on triton solubilised samples. Does not work in western blots. Produces antibodies with unique anti-gH neutralising properties.

 

Publications:

Buckmaster E.A., Cranage M.P., McLean C.S., Coombs R.R., Minson A. The use of monoclonal antibodies to differentiate isolates of herpes simplex types 1 and 2 by neutralisation and reverse passive haemagglutination tests.
J Med Virol. 1984 13:193–202.
http://eu.wiley.com/WileyCDA/WileyTitle/productCd-JMV.html

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Enquiry for Herpes Simplex Virus Glycoprotein H monoclonal antibody LP11 (anti-HSV gH)

Reagents Enquiry

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin-like growth factor 1 receptor monoclonal antibody IGF-1R 24-31

1 September, 2011 | Monoclonal hybridomas Code: AB6
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Hybridoma cell line producing IGF-1R 24-31 antibodies raised against human insulin-like growth factor 1 receptor (283-440 or 586-908 epitope), which are mouse monoclonal antibodies of the IgG1 isotype. Has been used in immunoprecipitation and blocking studies and causes

This reagent is available to license for internal research only.

Publications:

J Biol Chem (1992) 267: 12955. www.jbc.org/

J Biol Chem (1993) 268: 1087. www.jbc.org/

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Enquiry for Human insulin-like growth factor 1 receptor monoclonal antibody IGF-1R 24-31

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR CT-1

1 September, 2011 | Monoclonal hybridomas Code: AB4
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Hybridoma cell line producing IR CT-1 antibodies raised against the C-terminal portion of the human insulin receptor beta subunit, which are mouse monoclonal antibodies of the IgG1 isotype. Has been used in western blots and immunoprecipitation assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1992) 288, 195

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To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 83-14

1 September, 2011 | Monoclonal hybridomas Code: AB7
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Hybridoma cell line producing IR 83-14 antibodies raised against the alpha subunit of the human insulin receptor, which are mouse monoclonal antibodies of the IgG2a isotype. Has been shown to cause >80% inhibition of insulin binding and has been used in immunoprecipiatation and blocking assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 83-14

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To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 83-7

1 September, 2011 | Monoclonal hybridomas Code: AB29
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Hybridoma cell line producing IR 83-7 antibodies raised against the human insulin receptor, which are mouse monoclonal antibodies of the IgG1 isotype. Has been shown to cause enhancement of insulin binding and has been used in immunoprecipitation assays.

This reagent is available to license for internal research use only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 83-7

Reagents Enquiry

To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human insulin receptor monoclonal antibody IR 18-44

1 September, 2011 | Monoclonal hybridomas Code: AB28
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Hybridoma cell line producing IR 18-44 antibodies raised against the beta subunit of the human insulin receptor which are mouse monoclonal antibodies of the IgG2b isotype. Has has been shown to cause up to 50% inhibition of insulin binding and has been used in western blots, immunoprecipitation and blocking assays.

This reagent is available to license for internal research only.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Enquiry for Human insulin receptor monoclonal antibody IR 18-44

Reagents Enquiry

To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human CD18 monoclonal antibody YFC 118.12

30 June, 2011 | Monoclonal hybridomas Code: AB79
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Hybridoma cell line producing YFC118.12 antibodies raised against human CD18 which are rat monoclonal antibodies of the IgG2b isotype.

 

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Enquiry for Human CD18 monoclonal antibody YFC 118.12

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  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.

Human leukocyte antigen DR (HLA-DR) monoclonal antibody YAML 555.6

30 June, 2011 | Monoclonal hybridomas Code: AB75
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Hybridoma cell line producing YAML 555.6 antibodies raised against human leukocyte antigen DR (HLA-DR) which are rat monoclonal antibodies of the IgG2a isotype.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061

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Enquiry for Human leukocyte antigen DR (HLA-DR) monoclonal antibody YAML 555.6

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To find out more about how this website collects your personal data see www.enterprise.cam.ac.uk/about-us/information-compliance/data-protection/core-privacy-notices/website-users-use-personal-information/
  • In submitting your personal data via this form, you consent to being contacted via the details provided so that your enquiry can be responded to. A backup of your data will be held but only authorised individuals will be able to access your data. If you would like your data to be removed, please email support@thewebkitchen.co.uk.