Hybridoma cell line producing 15CH2 antibodies raised against human muscle creatine kinase which are mouse monoclonal antibodies of the IgG1 isotype. Useful for diagnosing tissue injury, especially myocardial infarction.
A non-exclusive licence with standard terms and conditions is available for this reagent.
Jackson, A. P., Siddle, K., and Thompson, R. J. Two-site monoclonal antibody assays for human heart- and brain-type creatine kinase. Clin Chem, 30: 1157–1162, 1984. www.clinchem.org/
Jackson, A. P. and Thompson, R. J. The stability of creatine kinase isoenzymes studied with two-site monoclonal antibody assays. Ann Clin Biochem, 22 ( Pt 3): 310–315, 1985
Rossi, R., Ekroth, R., Lincoln, C., Jackson, A. P., Thompson, R. J., Scallan, M., Tsang, V., Jackson, A., and Thompson, R. Detection of cerebral injury after total circulatory arrest and profound hypothermia by estimation of specific creatine kinase isoenzyme levels using monoclonal antibody techniques. Am J Cardiol, 58: 1236–1241, 1986. www.ajconline.org/
Thompson, R. J., Jackson, A. P., and Langlois, N. Circulating antibodies to mouse monoclonal immunoglobulins in normal subjects–incidence, species specificity, and effects on a two-site assay for creatine kinase-MB isoenzyme. Clin Chem, 32: 476–481, 1986. www.clinchem.org/