Available reagents

Licensing for the research community

Cell lines, antibodies, proteins, DNA constructs, small molecules and other research tools generated by scientists at the University of Cambridge play a key role in laboratory research. There is a wide range of research reagents available for commercial licensing through Cambridge Enterprise. The selection is constantly changing, so please contact us directly with your specific needs.

Non-exclusive licences with standard terms and conditions are available for available reagents.

Human insulin receptor monoclonal antibody IR 18-34

20 September, 2011 | Monoclonal hybridomas Code: AB3
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Hybridoma cell line producing IR 18-34 antibodies raised against the extracellular domain of the human insulin receptor which are mouse monoclonal antibodies of the IgG2a isotype. Has been shown to cross react very weakly with bovine, porcine and ovine but not rabbit, rat or mouse insulin receptors. It has been shown to cause up to 50% inhibition of insulin binding and has been used in immunohistochemistry, immunoprecipitation and blocking assays.

Publications:

Biochem J (1986) 235, 199

Biochem J (1987) 242, 123

EMBO J (1987) 6, 4003

Biochem J (1990) 268, 615

J Biol Chem (1990) 265, 9970. www.jbc.org/

J Biol Chem (1990) 265, 13248. www.jbc.org/

PNAS (1991) 88, 9858. www.pnas.org/

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Rat IgG2b monoclonal antibody NORIg 7.16.2

20 September, 2011 | Monoclonal hybridomas Code: AB71
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Hybridoma cell line against rat IgG2b, producing NORIg 7.16.2 antibodies which are mouse monoclonal antibodies.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061. http://www.jimmunol.org/

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Human HLA-class I monoclonal antibody YTH 862.2

20 September, 2011 | Monoclonal hybridomas Code: AB83
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Hybridoma cell line producing YTH 862.2 antibodies raised against human HLA-class I which are rat monoclonal antibodies of the IgG2b isotype.

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Human Leukocyte Antigen B (HLA-B) monoclonal antibody YTH 76.3

20 September, 2011 | Monoclonal hybridomas Code: AB74
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Human CD235a monoclonal antibody YTH 89.1

20 September, 2011 | Monoclonal hybridomas Code: AB66
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Hybridoma cell line producing YTH 89.1 antibodies raised against human CD235a which are rat monoclonal antibodies of the IgG2b isotype.

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Human CD66acd monoclonal antibody YTH 71.3

20 September, 2011 | Monoclonal hybridomas Code: AB64
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Hybridoma cell line producing YTH 71.3 antibodies raised against human CD66acd which are rat monoclonal antibodies of the IgG2a isotype.

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Human CD59 monoclonal antibody YTH 53.1

19 September, 2011 | Monoclonal hybridomas Code: AB114
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Hybridoma cell line producing YTH 53.1 antibodies raised against human CD59 which are rat monoclonal antibodies of the IgG2b isotype.

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Human CD45R monoclonal antibody YTH 80.103

19 September, 2011 | Monoclonal hybridomas Code: AB70
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Hybridoma cell line producing YTH 80.103 antibodies raised against human CD45R which are rat monoclonal antibodies of the IgG2b isotype.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061

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Human CD28 monoclonal antibody YTH 913.12

19 September, 2011 | Monoclonal hybridomas Code: AB113
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Hybridoma cell line producing YTH 913.12 antibodies raised against human CD28 which are rat monoclonal antibodies of the IgG2b isotype.

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Human CD25 monoclonal antibody YTH 906.9HL

19 September, 2011 | Monoclonal hybridomas Code: AB61
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Hybridoma cell line producing YTH 906.9HL antibodies raised against human CD25 which are rat monoclonal antibodies of the IgG2b isotype. The designation HL indicates that it has been selected for loss of the original Y3 myeloma derived (non-specific) light chain.

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Human CD16 monoclonal antibody YFC 120.5

19 September, 2011 | Monoclonal hybridomas Code: AB63
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Hybridoma cell line producing YFC 120.5 antibodies raised against human CD16 which are rat monoclonal antibodies of the IgG2b isotype.

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Human CD11a monoclonal antibody YTH 81.5

19 September, 2011 | Monoclonal hybridomas Code: AB82
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Hybridoma cell line producing YTH 81.5 antibodies raised against human CD11a which are rat monoclonal antibodies of the IgG2a isotype.

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Human CD7 monoclonal antibody YTH 30.15

19 September, 2011 | Monoclonal hybridomas Code: AB69
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Hybridoma cell line producing YTH 30.15 antibodies raised against human CD7 which are rat monoclonal antibodies of the IgG2b isotype.

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Mouse Thy-1 monoclonal antibody YTS 154.7.7.10

19 September, 2011 | Monoclonal hybridomas Code: AB10
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Hybridoma cell line producing YTS 154.7.7.10 antibodies raised against mouse Thy-1 which are rat monoclonal antibodies of the IgG2b isotype. Has been used in T+NK cell depletion in vivo and flow cytometry studies.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061

Cobbold S. & H. Waldmann (1986) Transplantation 41, 634

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Mouse heat stable antigen monoclonal antibody YBM 5.10.4

19 September, 2011 | Monoclonal hybridomas Code: AB72
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Hybridoma cell line producing YBM 5.10.4 antibodies raised against mouse heat stable antigen which are rat monoclonal antibodies of the IgG2c isotype.

Publications:

Journal of Immunology Vol 134 5 May 1985 pages 3056–3061

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Mouse CD71 monoclonal antibody YTA 74.4.4

19 September, 2011 | Monoclonal hybridomas Code: AB110
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Hybridoma cell line producing YTA 74.4.4 antibodies raised against mouse CD71 which are monoclonal antibodies of the IgG2a isotype. Has been used in CD4 subset depletion in vivo and flow cytometry studies.

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Mouse CD18 monoclonal antibody YTS 213.1.1

19 September, 2011 | Monoclonal hybridomas Code: AB109
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Hybridoma cell line producing YTS 213.1.1 antibodies raised against mouse CD18 which are rat monoclonal antibodies of the IgG2a isotype.

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Mouse CD8 (lyt-3) monoclonal antibody YTS 156.7.7

19 September, 2011 | Monoclonal hybridomas Code: AB15
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Hybridoma cell line producing YTS 156.7.7 antibodies raised against mouse CD8 (lyt-3) which are rat monoclonal antibodies of the IgG2b isotype. Has been used in CD8 subset depletion in vivo and flow cytometry studies.

Publications:

Qin, S., Cobbold, S., Bemjamin, R., & Waldmann, H.

J. Exp. Med. 169, 779–794 (1989) http://jem.rupress.org/

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Mouse CD8 (lyt-2) monoclonal antibody YTS 105.18.10

19 September, 2011 | Monoclonal hybridomas Code: AB112
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Hybridoma cell line producing YTS 105.18.10 antibodies raised against mouse CD8 (lyt-2) which are rat monoclonal antibodies of the IgG2a isotype.

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Mouse CD4 epitope B monoclonal antibody YTA 3.1.2

19 September, 2011 | Monoclonal hybridomas Code: AB13
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Hybridoma cell line producing YTA 3.1.2 antibodies raised against mouse CD4 Epitope B which are rat monoclonal antibodies of the IgG2b isotype. Has been used in CD4 subset depletion in vivo and flow cytometry studies.

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Mouse CD4 epitope A monoclonal antibody YTS 177.9.6.1

19 September, 2011 | Monoclonal hybridomas Code: AB111
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Hybridoma cell line producing YTS 177.9.6.1 antibodies raised against mouse CD4 epitope A which are rat monoclonal antibodies of the IgG2a isotype.

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Anti-4E3 antibody to human vascular endothelial growth factor A

19 September, 2011 | Monoclonal hybridomas Code: AB84
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Hybridoma cell line producing anti-4E3 antibodies raised against human vascular endothelial growth factor A (VEGF-A) which are mouse monoclonal antibodies of the IgG1 isotype. This antibody has been used for both in vitro and in vivo neutralisation assays.

Selected publications:

Sharkey, A. M. et al. Novel antiangiogenic agents for use in contraception (2005). Contraception 71, 263–271.

Sengupta, J. et al. Immunoneutralisation of vascular endothelial growth factor inhibits pregnancy establishment in the rhesus monkey (Macaca mulatta) (2007). Reproduction 133(6), 1199-1211.

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CD19 membrane protein of mouse B lymphocytes monoclonal antibody 6D5

19 September, 2011 | Monoclonal hybridomas Code: AB9
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Hybridoma cell line producing 6D5 antibodies rasied against CD19 membrane protein of mouse B lymphocytes which are rat monoclonal antibodies of the IgG2a isotype.

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E7 protein of human papillomavirus 16 monoclonal antibody CamVir-3

19 September, 2011 | Monoclonal hybridomas Code: AB56
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