Available reagents

Licensing for the research community

Cell lines, antibodies, proteins, DNA constructs, small molecules and other research tools generated by scientists at the University of Cambridge play a key role in laboratory research. There is a wide range of research reagents available for commercial licensing through Cambridge Enterprise. The selection is constantly changing, so please contact us directly with your specific needs.

Non-exclusive licences with standard terms and conditions are available for available reagents.

We are currently seeing increased interest in our research reagents portfolio as biotech companies respond to the COVID-19 crisis. You can read our blog on this topic here.

CRISPR Cas9D10A nickase-based genotypic and phenotypic screening to enhance genome editing

25 May, 2016 | Plasmids Code: Undisclosed
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A CRISPR Cas9D10A-based screening approach that combines an All-in-One Cas9D10A nickase vector with fluorescence-activated cell sorting enrichment has been developed in the lab of Prof Steve Jackson at the University of Cambridge. The technique is combined with high-throughput genotypic and phenotypic clonal screening strategies to generate isogenic knockouts and knock-ins highly efficiently, which leads to minimal off-target effects. Please see the published paper describing the technology below:

Chiang, T.-W. W., le Sage, C., Larrieu, D., Demir, M. and Jackson, S. P. Sci Rep. 2016, 6, 24356.

Please get in touch if you would like more information.

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