Method for single nucleotide resolution mapping of abasic (AP) sites

Ref No: Bal-3454-17

Prof. Sir Shankar Balasubramanian and his team have developed a novel method for single nucleotide resolution mapping of AP sites (including endogenous sites) in genomic DNA. The method uses a novel probe, with selectivity >200 fold relative to 5-fU and >2000 fold relative to 5-fC for use in epigenetics research.

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