Feasibility studies, pilot studies and Phase II trials are viewed as purpose-driven preparatory studies, essential for determining the most appropriate questions for the next generation of Phase III trials. The Feasibility Study Project Grants scheme funds studies testing aspects of feasibility or tolerability and/or efficacy.

Cancer Research UK accepts investigator-led studies, except first in man studies, including:

- Single or multi-centre prospective therapeutic (IMP and non-IMP), diagnostic or prevention phase II studies testing aspects of feasibility, tolerability and/or efficacy. Trials may involve more than one NCRN network, or several centres within a network.

- Academically-led feasibility studies in receipt of educational grants or free drugs from the pharmaceutical industry can be submitted for endorsement (industry-sponsored trials cannot be reviewed under this scheme).

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