PC12 (rat phaeochromocytoma) HD-Q23 (lines 14 and 7)

PC12 (rat phaeochromocytoma) HD-Q23 (lines 14 and 7)

Code: CL4

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Inducible lines in PC12 (rat phaeochromocytoma) cells which express a GFP-tagged exon 1 fragment of the HD gene with 23 glutamine repeats (cell lines 14 and 7), driven by a doxycycline (dox)-dependent Tet-On promoter. Useful in in-vitro assay development for neurodegenerative diseases.

Publications:

Wyttenbach et al, Human Mol Genet (2001)10: 1829-1845. http://hmg.oxfordjournals.org/

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